See the International Space Station from your house?http://spotthestation.nasa.gov/
If you are an Amateur (Ham) radio operator you could talk to the astronauts on board.
If you are not but have a radio scanner you can hear them. Just listen on 145.800 & or 145.825 FM mode. You can get further information at:http://spaceflight.nasa.gov/station/reference/radio/
I have made contact with the ISS and received their QSL card.
See a larger photos at:
QSL Front
QSL Back